An exciting new mouse study performed by researchers at the Mayo Clinic may provide hope for delaying signs of aging and aging related discomforts and disease in the future.
Cells normally produce additional cells throughout their life cycle. Senescent cells, also called deadbeat cells, are cells that are still alive but are no longer multiplying. Senescent cells produce factors that harm the nearby cells, and as a result cause tissue inflammation.
The researchers at Mayo used genetically engineered mice to identify the impact of removing senescent cells on the aging process and age-related disease.
The mice in the study were genetically engineered to carry caspase 8, a molecule that only turns on when the mice are given a drug that has no effect on normal cells. When the mice were given the drug, caspase 8 became active within the senescent cells and effectively killed them.
The researchers found that when these cells were eliminated, the onset of age-related disorders was delayed. Also, when those cells were removed, the progress of age-related disorders already underway were significantly slowed.
For much more about this study and the implications, including aging and wrinkles, please visit http://www.medicalnewstoday.com/articles/237023.php.











