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Wed, July 1, 2009
Gene Linked To Gout
A team at Johns Hopkins have identified a gene called ABCG2 that plays a role in gout, which affects nearly 3 million Americans. Although the gene is not the only factor causing gout, the scientists believe a malfunction in this gene could affect nearly 10% of Caucasians who suffer from this disease.

The ABCG2 gene is responsible to carry urate out of the system and into the urine. Too much urate in the system can cause crystals to form in joint tissue, which can cause a lot of pain and inflammation for those inflicted.

The study shows that a mutation in this gene can cause the urate to leave the cells at less than half the rate. The discovery is promising as until now the focus for eliminating this issue is to diminish urate production rather than target the gene that targets delivery of the “urate transporter” protein.

For more information on this exciting new research, please visit http://www.news-medical.net/news/0090618/Gout-gene-discovered.aspx.

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